Jaundice and its types
Jaundice is a clinical condition characterized by the yellow color of the white of the eyes (sclera) and skin. It is caused by the deposition...
Virulence factors of Bordetella pertussis
Bordetella pertussis is a small non-motile, non-sporing ovoid. Gram negative cocco-bacillus. It measures about 1-1.5µm x 0.3µm and is haemolytic. Capsulated (fresh isolates from patients),...
Pathogenesis of Gonococcal infection
Gonococcus is considered to be a strict human parasite. Various attempts were done to infect animals. But all had failed until recently when chimpanzees have...
Pathogenesis of Haemophilus influenzae
The non-capsulated variety of Haemophilus influnzae is a very common commensal in upper respiratory tract. 60-80% cases have been found related to non-capsulated strains in...
Determinants of pathogenicity of Clostridium botulinum
Botulism literally stands for sausage (botulus, Latin- sausage). The food poisoning in early days was generally caused by ingestion of poorly cooked sausage. Clostridium...
Virulence factors of Group-A Streptococcus
Streptococcus are gram positive, catalase negative cocci. Are spherical or ovoid, 0.5-1µ in diameter, arranged in chains, non-motile and non-sporing. They may become gram negative...
Determinants of antigenicity
Antigenicity is the ability to combine specifically with the final products of the responses i.e. secreted antibodies and/or surface receptors on T cells. All molecules...
Pathogenesis of Vibrio cholera
The sequence of events leading to cholera is basically simple and confined to the gut. The food and drink contaminated by cholera vibrios if ingested...
Widal test: Procedure, Interpretation
It is a type of agglutination test. This test is used to detect presence of serum agglutinins (H and O) in patient’s serum with typhoid...
Immunoglobulin M (IgM): Structure and Properties
Properties This type of immunoglobulin accounts or constitutes 5-10% of total serum immunoglobulin in adults. The serum concentration is 5-2 mg per 100 ml. The...