Stages and Features of Antigen-Antibody Reactions

Stages and Features of Antigen -Antibody reaction

Introduction The combination of antigens (Ag) and antibodies (Abs) occur specifically and in observable manner. There is various usefulness of this type of reaction. Some of them are: A basis for the formation of antibody mediated immunity Helps generally during the cases of infectious diseases. Besides, in tissue injury related to some types of hypersensitivity … Read more

Determinants of antigenicity

Antigenicity is the ability to combine specifically with the final products of the responses i.e. secreted antibodies and/or surface receptors on T cells. All molecules having the property of immunogenicity also have the property of antigenicity but the reverse is not true. Some small molecules are antigenic but they are not able to induce a … Read more

ELISA and its type

It is the abbreviated form of Enzyme-linked immunosorbent assay or EIA. It is similar in principle to Radio immune assay (RIA) but instead of radioactive substance it uses an enzyme. Chromogenic substrate is generated by reacting an enzyme conjugated with the antibody and a colorless substrate. Chromogenic substrate is a colored reaction product. Various enzymes … Read more

Antigenic determinants on immunoglobulins

Immunoglobulin molecules themselves function as potent immunogens when they are introduced into other animal species to induce an antibody response. For studying the B cell development and humoral immune response, such anti-Ig antibodies are considered to be a powerful tool. The antigenic determinants are also called epitopes on immunoglobulin molecules. They are categorized into three … Read more

Differences between antigens and antibodies

S.N Antigens Antibodies 1. Commonly called “antibodies generating chemicals” or immunogens. Commonly called immunoglobulins. 2. Both proteinous or polysachharides. Always proteinous in nature. 3. They are present on the cell membrane. They are present in the plasma. 4. These stimulate the immunity of the body. These protect the body from infections. 5. May be a … Read more