| Points of difference | Unstriped muscles | Striped muscles | Cardiac muscles | |
| 1. location | In the walls of hollow internal organs, like stomach, intestine, etc | Attached to the skeleton | In the walls of heart. | |
| 2. shape | Elongated, spindle- shaped, tapering at both ends. | Long, cylindrical, non tapering, unbranched | Elongated, cylindrical and branched. | |
| 3. arrangement | Arranged in tubes. | In bundles | Forming a network | |
| 4. sarcolemma | True sarcolemma not found | present | present | |
| 5. nucleus | Uninucleate, and central nucleus | Multinucleate, and peripheral nucleus | Many nuclei between successive end plates | |
| 6. cytoplasmic contents | Less mitochondria and glycogen granules | Numerous mitochondria and glycogen granules | Numerous and large mitochondria and glycogen granules faintly present | |
| 7. striations | absent | present | Faintly present | |
| 8. blood supply | poor | rich | rich | |
| 9. myofibrils | Smaller and indistinct | Larger and much greater in number | Myofibrils are visible | |
| 10. nerve supply | From autonomous nervous system | Have both motor and sensory nerve endings from central nervous system | From autonomous nervous system | |
| 11. mode of working | involuntary | voluntary | Myogenic | |
| 12. contractions | Slow and rhythmic with long resting period | Rapid with short resting period | Continuous and rhythmically | |
| 13. tiredness | Do not get tired easily | Becomes tired easily | Do not get tired | |
| 14. energy demand | Much less and constantly | High and at a time | High and constantly | |

Image source: brainkart
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