Various endocrinal disorders

Hormone Excess Defeciency
Growth hormone or somatotrophin  hormone (STH) Gigantism in children

Acromegaly in adult.

Thyroid stimulating hormone/thyrotropin (TSH) Increases the activity of thyroid gland called hyperthyroidism. Decreases the activity of thyroid gland called hypothyroidism.
Prolactin Infertility, galactorrhoea, amenorrhea and decreased libido in male. Hypoprolactinaemia.
Vasopressin Increase the osmolarity of urine. Diabetes insipidus.
Thyroid hormone Grave’s disease, exophthalmic goiter characterized by palpitation, sweating, weight loss, heat intolerance, diarrhea, anxiety, tremor, tachycardia. Myxedema in adults and cretinism in children characterized by cold intolerance, constipation, bradycardia, dry coarse skin, sluggish movements.

Cretin babies are dwarf and mentally retarded.

Hashimoto’s thyroiditis is an autoimmune disease..

Para-thormone Weak bone that can fracture easily, stone formation. Hypo-calcemia leading to tetany.
Aldosterone Conn’s syndrome leading to hypertension, hypokalemia, hypernatremia and metabolic alkalosis. Hyponatremia, hyperkalemia, shock and metabolic acidosis.
Glucocorticoids Cushing’s syndrome–  moon face, buffalo hump, osteoporosis, hypertension and inhibition of growth. Addison’s disease– hypotension, hyperpigmentation.
Androgen Hirustism and virilization, pseudo  hermaphroditism in female, precocious  puberty in males. Decreased libido in male and pseudo hermaphroditism in male
Estrogen Increase risk of thrombosis and breast cancer, decrease FSH secretion and interfere with implantation. Abnormal menstrual cycle, ill developed genital tracts.
Progesterone Prevents ovulation leading to  anovulatory cycle. Abnormal menstrual cycle, pregnancy does not occur.

Endocrine System- Definition, Glands, Hormones, Functions, Disorders

 Image source: thebiologynotes





Various endocrinal disorders