The chemical process in which there is transfer of an amino (-NH2) group from an amino acid to a keto-acid is known as transamination. This process involves the inter conversion of a pair of amino acids and a pair of keto acids which are catalyzed by a group of enzymes called transaminases (recently called aminotransferases). … Read more
Gout is a metabolic disease which is associated with overproduction of uric acid. Uric acid is found in a more soluble form as sodium urate at the physiological pH. Crystals of sodium urate get deposited in the soft tissues particularly in the joints in case of severe hyperuricemia. Such deposits are commonly called tophi. This … Read more
Vitamin C is a water soluble versatile vitamin. It has important role in human health and disease. It has become the most controversial vitamin in the recent years. Its controversy is due to the claims and counterclaims on the use of it in mega-doses to cure everything from common cold to cancer. The disease associated … Read more
Urea is considered as the end product of protein metabolism (amino acid metabolism). The nitrogen of amino acids gets converted to ammonia which is toxic to the body. It is then converted to urea and detoxified. Such urea accounts for 80-90% of the nitrogen containing substances which is excreted in the urine. It is synthesized … Read more
All the enzymes that are involved in biological oxidation belong to the class oxidoreductases. In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule called the reductant, also known as the electron donor, to another called the oxidant ( also known as the electron acceptor). These are further categorized into four groups. A) Oxidases B) Dehydrogenases C) Hydroperoxidases D) Oxygenases … Read more