Virulence factors of Bordetella pertussis

Bordetella pertussis is a small non-motile, non-sporing ovoid. Gram negative cocco-bacillus. It measures about 1-1.5µm x 0.3µm and is haemolytic. Capsulated (fresh isolates from patients), strict aerobes and fastidious. On staining with toludine blue, metachromatic granules are seen. The genes coding for B. pertussis virulence factors are under the control of two sets of genes, which … Read more

Blood and its composition

red coloured fluid connective tissue. Alkaline and salty in taste (pH 7.35-7.45). 7-8% of body weight. Average volume is 5-6 litres in male and 4-5 litres in female. Slightly denser than water (1.043-1.060 gm/ml). 5 times more viscous than water. Red due to presence of haemoglobin. Temperature – 100.4°F. Made up of plasma (55%) and … Read more