Alternative pathway of complement system

Alternative pathway of complement system

Alternative Pathway The alternate pathway bypasses C1, C4, C2 components and starts at C3 step. It is generally activated by non-immunological means such as bacterial surfaces and their components (e.g. endotoxin, microbial polysaccharides). Some other factors such as inulin, zymosan, yeast walls, cobra venom are also responsible for activation of this pathway. However, the mechanism … Read more

Classical complement pathway

Classical complement pathway

Introduction to Complement Complement is the name given to a system of some non-specific proteins present in normal human and animal serum. These proteins have got the ability to lyse or damage cells (bacteria, virus, tumour cells) and to stimulate some antigen and antibody reactions. This system consists of approximately 20 serum proteins which include … Read more