Alternative pathway of complement system

Alternative pathway of complement system

Alternative Pathway The alternate pathway bypasses C1, C4, C2 components and starts at C3 step. It is generally activated by non-immunological means such as bacterial surfaces and their components (e.g. endotoxin, microbial polysaccharides). Some other factors such as inulin, zymosan, yeast walls, cobra venom are also responsible for activation of this pathway. However, the mechanism … Read more

Immunodeficiency and its type

Immunodeficiency and its type

Introduction Immunodeficiency diseases are condition where the defense mechanism of the body is impaired lading to repeated microbial infections of varying severity and sometimes enhanced susceptibility to malignancies. In this condition, the system fails to protect the host from disease causing agents or from malignant cells. Deficiency of defense mechanism may include:  Specific immune functions … Read more