polysaccharides

Determinants of antigenicity

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Antigenicity is the ability to combine specifically with the final products of the responses i.e. secreted antibodies and/or surface receptors on T cells. All molecules having the property of immunogenicity also have the property of antigenicity but the reverse is not true. Some small molecules are antigenic but they are not able to induce a … Read more

Alternative pathway of complement system

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Alternative pathway of complement system

Alternative Pathway The alternate pathway bypasses C1, C4, C2 components and starts at C3 step. It is generally activated by non-immunological means such as bacterial surfaces and their components (e.g. endotoxin, microbial polysaccharides). Some other factors such as inulin, zymosan, yeast walls, cobra venom are also responsible for activation of this pathway. However, the mechanism … Read more