Introduction A condition resulted by the action of antibodies or immunologically competent cells. Cause structural or functional damage of the normal components of the body. Literally means ‘protection against self’ but means ‘injury to self’ in actual. Ehrlich postulated the concept of horror auto-toxicus. Was proposed while observing goats producing antibodies against erythrocytes from other … Read more
Antigenicity is the ability to combine specifically with the final products of the responses i.e. secreted antibodies and/or surface receptors on T cells. All molecules having the property of immunogenicity also have the property of antigenicity but the reverse is not true. Some small molecules are antigenic but they are not able to induce a … Read more
Properties This type of immunoglobulin accounts or constitutes 5-10% of total serum immunoglobulin in adults. The serum concentration is 5-2 mg per 100 ml. The half-life of IgM is about 5 days. It can be produced in a T-independent manner. Monomeric IgM has molecular weight of 180,000 Da which is expressed as membrane bound antibody … Read more
S.N Antigens Antibodies 1. Commonly called “antibodies generating chemicals” or immunogens. Commonly called immunoglobulins. 2. Both proteinous or polysachharides. Always proteinous in nature. 3. They are present on the cell membrane. They are present in the plasma. 4. These stimulate the immunity of the body. These protect the body from infections. 5. May be a … Read more